RESEARCH CENTRE; registration number: 00000966/ARDA/J06/ALPAS/APPB
39 Rue Marcus ETOUNDI P.O. Box 13591 Yaoundé, Cameroon
Tel +237 673 086 046 http://www.crid-cam.net
CENTRE FOR RESEARCH IN INFECTIOUS DISEASES

JOB ADVERTISEMENT : Therapeutic Study Monitor (TSM) – CENTRE FOR RESEARCH IN INFECTIOUS DISEASES, Yaoundé and Garoua

JOB DESCRIPTION
Therapeutic Study Monitor
JOB TITLE : Therapeutic Study Monitor (TSM)
REPORT TO : Head of Department of
Parasitology and Microbiology
POSITION TYPE: Fixed term contract
DURATION : 02 Years
JOB LOCATION : Yaoundé and Garoua
Job purpose: We are seeking a Therapeutic Study Monitor (TSM) as part of a five-year USAID-funded
Systems to End the Malaria Burden through Meaningful Engagement-II (SEMBE II) Project in

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Cameroon. The project seeks to strengthen the capacity of the Cameroonian government and local

stakeholders to positively respond to malaria prevention, control, and elimination priorities.
The TSM will be involved on the implementation of a therapeutic efficacy study (TES) of Artemisinin-
based combination therapy (ACT) for malaria treatment in the north region (Cameroon). The TSM
will work under the authority of the Head of department of Parasitology and Microbiology, acting also
as Study Director of the SEMBE II project at CRID.
Primary Responsibilities:
Specifically, the Therapeutic Study Monitor would undertake the following activities:
 Write the protocol of the study and submit it to the National ethical committee and the
Direction of operational research for health (DROS) of the MoH to obtain the ethical
clearance and the administrative authorization, respectively;
 Conduct controlled studies to assess the effectiveness of antimalarial drugs;
 Verify the origin and quality of the drugs administered to patients;
 Ensure data quality and regulatory compliance at every stage of the study process;
 Ensure the continuous follow-up of the study in the participating health facilities

 Ensure the recruitment and the training of the nurses who will be involved in the TES;
 Evaluate patients’ clinical and parasitological responses to treatment for uncomplicated
malaria;
 Ensure that the inclusion of participants to the study in accordance with procedures and
criteria described in the protocol;
 Ensure adherence to procedure and Good Clinical Practice (GCP) throughout the study ;
 Verify signatures of informed consents, compliance with inclusion and exclusion criteria;
 Ensure the reliability and completeness of the data collected on the monitoring sheets
reports by nurses;
 Identify obstacles and malfunctions in the implementation of the study and propose
corrective actions;
 Ensure the data collected during the study is entered on a computer and/or tablet

 Ensure the transfer of blood samples (blood smears and dried blood spot) from the field to

laboratory at CRID for both microscopic and molecular analyses;
 Supervise the laboratory analyses of blood samples collected at the health facilities;
 Ensure data management: validation, analysis, archiving;
 Write technical reports
SKILLS AND REQUIREMENTS QUALITIES NEEDED:
 Medical doctor with good experience on epidemiological studies;
 At least 1 year work experience related to malaria;
 Good knowledge on malaria diagnosis
 Familiarity with antimalarial drug research and relevant therapeutic areas is advantageous;
 Prior experience in clinical research or monitoring roles is advantageous;
 A solid understanding of clinical research principles, study protocols, and Good Clinical
Practice (GCP) guidelines is essential;
 Strong organizational skills are necessary to manage study timelines, site visits, and
documentation;
 Ability to analyse clinical data, identify trends, and assess drug efficacy;
 Capacity to interpret laboratory results and clinical outcomes;
 Data analysis skills and competency in statistical software such as R, SPSS or Stata are
preferred;
 Good knowledge of survival analysis using the Kaplan-Meier method;
 Very good knowledge of malaria control strategies in Cameroon;

 Very good knowledge on the management of malaria cases by ACTs in Cameroon;
 Proficiency in MS Office packages (Excel, Word, PowerPoint), Web Conferencing
Applications, knowledge-sharing networks is required;
 Excellent communication skills (writing and oral presentation) and a demonstrated track
record of working effectively in a teamwork environment, highly desirable;
 A good command of French and English languages is required.

Work Environment
• The TSM will be based at CRID in Yaoundé but will have to stay at least half of his time in the North
Region (visiting health facilities in the 15 health districts of the region)

Application instructions:
 Curriculum vitae
 Cover letter (letter of motivation)
 Photocopy of degrees
 At least two professional references
Deadline for receiving applications: May 25th, 2024
Kindly send your application in file in an unique PDF file to the following address: crid@crid-
cam.net